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A study done several years ago showed that over a two-year period, less than 20 of patients on allopurinol were taking it as prescribed.

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caution, however, needs to be exercised inasmuch as the reported frequency of adverse events leading to discontinuation of the drug occurred two and three times as often in the low-dose and high-dose febuxostat groups, respectively, as in the allopurinol group.

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